Serum matrix metalloproteinases MMP-9 and MMP-2 and tissue inhibitors TIMP-2 in necrotizing enterocolitis
نویسندگان
چکیده
The analysis of the balance elastase (MMP-2, MMP-9) and TIMP-4 was performed in order to determine their involvement pathogenesis NEC. A progressive duration NEC with sepsis is accompanied by increased serum concentrations MMP-9, MMP-2 TIMP-4. Increases MMP-2>503 ng/ml, MMP-9>812 ng/ml TIMP-4>1404 can be regarded as statistically significant predictors fatal outcome proposed method for determination outcomes newborns characterized high sensitivity (94%) specificity (87%).
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ژورنال
عنوان ژورنال: Journal of Pediatrics & Neonatal Care
سال: 2021
ISSN: ['2373-4426']
DOI: https://doi.org/10.15406/jpnc.2021.11.00438